This highly effective supplement has been used safely in conjunction with hypertensive pharmaceuticals to maintain normal blood pressure. As blood pressure improves, as seen in over 80% of cases, the pharmaceutical(s) may be reduced accordingly, with the help of prescribing physician. With several years of experience with BPNatRelief, there has never been a reported problems with interference with a hypertensive drug or a reported side effect using this supplement. It is the unique (proprietary) formulation of this product, coming from centuries of use that makes it so effective and safe.